CAS 186028-79-5 bkebdp mdmc white crystal research chemical for
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Ethylone, or 3,4-methylenedioxy-N-ethylcathinone, is a synthetic
molecule of the cathinone family. Cathinones are structurally
similar to amphetamines in that they contain a phenethylamine core
featuring a phenyl ring bound to an amino (NH2) group through an
ethyl chain with an additional methyl substitution at Rα.
contains an ethyl substitution at RN, a substitution which is
shared with drugs like MDEA, 4-MEC, and certain other stimulants
ethylone contains substitutions at R3 and R4 of the phenyl ring
with oxygen groups. These oxygen groups are incorporated into a
methylenedioxy ring through a methylene chain. Ethylone shares this
methylenedioxy ring with MDA, MDAI and MDME.
Ethylone acts as a mixed reuptake inhibitor/releasing agent of
serotonin, norepinephrine, and dopamine.These are the
neurotransmitters in charge of pleasure, reward, motivation and
This is done by inhibiting the reuptake and reabsorption of the
neurotransmitters after they have performed their function of
transmitting a neural impulse, essentially allowing them to
accumulate and be reused, causing physically stimulating and
In comparison to methylone, it has approximately over 3x lower
affinity for the serotonin transporter (which itself has 3x lower
affinity than MDMA), while its affinity for the norepinephrine and
dopamine transporters is similar.
The results of these differences in pharmacology relative to
methylone is that ethylone is less potent in terms of dose, has
more balanced catecholaminergic effects relative to serotonergic,
and behaves more like a reuptake inhibitor like methylphenidate
than a releaser like amphetamine; however, ethylone still has
relatively robust releasing capabilities.
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